{"product_id":"egcg-stabilized-selenium-nanoparticles","title":"EGCG stabilized selenium nanoparticles","description":"\u003cp\u003eProduct Name EGCG stabilized selenium nanoparticles Product Overview EGCG stabilized selenium nanoparticles (EGCG SeNPs) are a type of functional nano selenium material prepared by green synthesis method using epigallocatechin gallate (EGCG), the main active ingredient in green tea, as a surface stabilizer. Compared to traditional selenium nanoparticles, EGCG SeNPs combine the high biological activity of nano selenium with the pharmacological properties of EGCG, making them a research hotspot in the fields of biomedical, antioxidant, anti-inflammatory, antibacterial, and functional formulation nanomaterials. EGCG is firmly bound to the surface of selenium nanoparticles through Se-O coordination bonds and hydrogen bonding, forming a dense organic coating layer, achieving size control, morphology regularity, and colloidal stabilization of nanoparticles, avoiding the shortcomings of easy aggregation, oxidation, and poor storage stability of bare selenium nanoparticles. Technical Parameter Concentration:1 mg\/mL(以硒纳米颗粒浓度计算) Solvent : Water Diameter 8-20 nm(TEM) Stabilizer :EGCG Appearance: Red solution Zeta:-0.25 mV Product Features 1) Chemical stability: Bare selenium nanoparticles have a large specific surface area and high surface energy, making them prone to aggregation, oxidation, and deactivation. The surface coating structure of EGCG can effectively isolate oxygen and solvent molecules, suppress particle fusion and selenium valence state transition, and greatly improve in vitro storage stability and in vivo physiological environment stability. 2) Good biocompatibility: EGCG surface modification can reduce the cytotoxicity of nano selenium and enhance its biodegradability. 3) Surface functionalization: Selenium nanoparticles retain a large number of active hydroxyl groups and binding sites on their surface, which can further couple with targeted peptides, antibodies, and small molecule ligands to construct targeted intelligent nanosystems. Application Fields 1) Antioxidant and oxidative stress regulation: EGCG SeNPs can efficiently clear intracellular reactive oxygen species (ROS), activate the Keap1\/Nrf2 antioxidant pathway, upregulate antioxidant protein expression, alleviate oxidative damage, protect mitochondrial homeostasis, and significantly improve oxidative stress-induced cell apoptosis and tissue damage. 2) Neuroprotective and anti apoptotic effects: EGCG SeNPs can protect nerve cells, inhibit β - amyloid protein aggregation, and reduce neurotoxicity. They have good neural repair and functional recovery effects in models of cerebral ischemia, spinal cord injury, depression, and neurodegenerative diseases, and are highly promising neuroprotective nanomaterials. 3) Antibacterial and biosafety materials: can be used to prepare antibacterial dressings and preservation coatings, applied to fresh food preservation and wound antibacterial care.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"5ml S:water,C:1mg\/mL,Size:8-20 nm 110809 \/ Store at 4°C refrigerated \/ 30days","offer_id":57280560365946,"sku":"110809","price":562.5,"currency_code":"USD","in_stock":true},{"title":"10ml S:water,C:1mg\/mL,Size:8-20 nm 110810 \/ Store at 4°C refrigerated \/ 30days","offer_id":57280560398714,"sku":"110810","price":937.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/es\/products\/egcg-stabilized-selenium-nanoparticles","provider":"xfnano","version":"1.0","type":"link"}