Liposome-Nanostructured lipid carriers

Product Overview Nanostructured Lipid Carriers (NLC) is a new generation of lipid nanoparticle delivery system developed on the basis of the first generation of lipid nanoparticles - Solid Lipid Nanoparticles (SLN). NLC is a binary lipid matrix system composed of a blend of solid and liquid lipids. By introducing a mixture of liquid and solid lipids and utilizing the steric hindrance effect between solid-liquid lipid molecules, the ordered arrangement of crystals is disrupted, resulting in defective or amorphous structures. Technical Parameter Concentration:10 mg/mL Solvent:Water Diameter:200-300 nm(TEM) Emulsifier:Span-20,Tween-80,Lecithin Diameter:White transparent solution Product Features 1) Excellent physical and chemical stability: The liquid lipid component of NLC significantly reduces the Gibbs free energy of the system, effectively inhibits the lipid recrystallization process, and delays the polymorphic transformation. 2) Targeted delivery: NLC itself has a certain passive targeting effect on the lungs and can achieve active targeted delivery through ligand modification. 3) Small particle size and easy surface modification: NLC has a nanoscale particle size and is easy to functionalize on the surface, such as ligand modification, which can achieve targeted delivery and further improve treatment accuracy. Good biocompatibility and safety: NLC is composed of biodegradable lipid materials, which have good biocompatibility and biodegradability. Application Fields 1) Medical field: Medicine is the most widely and deeply applied field of NLC, such as through passive and active targeting strategies, NLC can be used for precision tumor treatment. In addition, NLC is considered a promising oral delivery carrier that can significantly improve the oral bioavailability of hydrophobic drugs. 2) In the field of cosmetics, NLC can be used as a sunscreen carrier, active substance carrier, and sustained-release carrier to effectively protect and deliver the active ingredients in cosmetics.NLC can enhance skin hydration and promote transdermal drug absorption. 3) In the field of food and functional foods, NLC has been widely used for the embedding and delivery of bioactive ingredients such as essential fatty acids, carotenoids, plant sterols, fat soluble vitamins, and polyphenolic compounds.