{"product_id":"peg-modified-gold-nanoparticles","title":"PEG modified gold nanoparticles","description":"\u003cp\u003eProduct Name PEG modified gold nanoparticles Product Overview PEG modified gold nanoparticles generally use thiolated PEG, anchored on the surface of gold nanoparticles by gold sulfur bonds, forming a hydrated polymer shell layer, effectively solving the core defects of bare gold nanoparticles such as easy aggregation, easy adsorption of impurities, short half-life of in vivo circulation, and strong non-specific interference in complex biological environments. It is a key surface modification technology for realizing the biomedical transformation of gold nanoparticles and has been widely used in multiple biomedical fields such as biosensing, medical imaging, tumor therapy, drug delivery, etc. In addition, PEG end can flexibly modify various functional groups such as methoxy, carboxyl, amino, biotin, etc., which can conveniently covalently couple functional molecules such as targeted peptides, specific antibodies, chemotherapy drugs, fluorescent probes, etc., achieving multifunctional integration of single nanoparticle targeted recognition, drug loading, signal imaging, precision therapy, etc., and the modification process will not damage the inherent surface plasmon resonance optical properties and photothermal conversion performance of the gold core. This product is modified with PEG on the basis of XFJ60. For the parameters of gold nanoparticles, please refer to XFJ60. Our company can also provide polyethylene glycol modified gold nanoparticles with carboxyl, amino, and hydroxyl end groups. Technical Parameter Concentration: 0.05 mg\/mL; Diameter: 5 nm 8 nm; 10 nm 15 nm; 20 nm 25 nm; 30 nm 40 nm; 50 nm 60 nm; 70 nm 80 nm; 90 nm 100 nm Appearance: Wine red solution Product Features 1) Excellent colloidal stability: PEG chains form a spatially hindered hydration layer, which inhibits the aggregation and sedimentation of gold nanoparticles in complex physiological environments such as high salt, serum, and cell culture media; Compared to sodium citrate bare gold nanoparticles, it has higher ion strength tolerance and better storage stability. 2) Surface multifunctionality: PEG can choose different end groups such as carboxyl, amino, biotin, etc., which facilitates covalent coupling of antibodies, peptides, small molecule drugs, fluorescent dyes, and enables the same particle to have multiple functions such as imaging, targeting, and drug loading simultaneously. 3) Good biocompatibility: Gold core itself is chemically inert, PEG has low biological toxicity, and weak in vitro cytotoxicity. Application Fields 1) In vitro biomarker: PEG AuNPs conjugated antibody, compared to bare gold, has less aggregation in cell and tissue samples and lower labeling background. 2) Biosensing and Immunoassay: Used for ELISA, immunochromatography, electrochemical sensors. PEG modification inhibits non-specific protein adsorption, reduces background interference, and improves detection sensitivity. It can be used for tumor biomarker and protein molecule detection. 3) Biomedical imaging contrast: Atomic X-rays have a high attenuation coefficient, PEG AuNPs are used as CT contrast agents, and long circulation is beneficial for vascular imaging and tumor visualization.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 mL D:5nm,C:0.05mg\/ml,water 111346 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589070714,"sku":"111346","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:8nm,C:0.05mg\/ml,water 111347 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589103482,"sku":"111347","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:10nm,C:0.05mg\/ml,water 111348 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589136250,"sku":"111348","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:15nm,C:0.05mg\/ml,water 111349 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589169018,"sku":"111349","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:20nm,C:0.05mg\/ml,water 111350 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589201786,"sku":"111350","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:25nm,C:0.05mg\/ml,water 111351 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589234554,"sku":"111351","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:30nm,C:0.05mg\/ml,water 111352 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589267322,"sku":"111352","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:40nm,C:0.05mg\/ml,water 111353 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589300090,"sku":"111353","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:50nm,C:0.05mg\/ml,water 111354 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589332858,"sku":"111354","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:60nm,C:0.05mg\/ml,water 111355 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589365626,"sku":"111355","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:70nm,C:0.05mg\/ml,water 111356 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589398394,"sku":"111356","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:80nm,C:0.05mg\/ml,water 111357 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589431162,"sku":"111357","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:90nm,C:0.05mg\/ml,water 111358 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589463930,"sku":"111358","price":234.38,"currency_code":"USD","in_stock":true},{"title":"10 mL D:100nm,C:0.05mg\/ml,water 111359 \/ Store at 4°C refrigerated \/ 180days","offer_id":57280589496698,"sku":"111359","price":234.38,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/es\/products\/peg-modified-gold-nanoparticles","provider":"xfnano","version":"1.0","type":"link"}