{"product_id":"recombinant-mouse-il-12-beta-protein-his-tag","title":"Recombinant Mouse IL-12 beta Protein (His-tag)","description":"\u003cp\u003eDESCRIPTION Synonym IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 Species Mouse Accession P43432 Source HEK293 cells SPECIFICATIONS Amino acid sequence Met23-Ser335 is expressed with a 10×His tag at the C terminus Molecular Weight 37.2 kDa Purity \u0026gt;95.0% as determined by SDS-PAGE Endotoxin \u0026lt;5 EU·mg-1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND Subunit beta of interleukin 12 (IL12B) is a subunit of human interleukin 12. Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK\/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B\/IL-12B is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine is important for sustaining a sufficient number of memory\/effector Th1 cells to mediate long-term protection to an intracellular pathogen. IL12B Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. Data SDS-PAGE Bioactivity Active Recombinant Mouse IL-12 beta Protein was determined by SDS-PAGE with Coomassie Blue.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 μg IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 106032 \/ Store at -20°C \/ 365days","offer_id":57280522617210,"sku":"106032","price":134.38,"currency_code":"USD","in_stock":true},{"title":"100 μg IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 106033 \/ Store at -20°C \/ 365days","offer_id":57280522649978,"sku":"106033","price":670.31,"currency_code":"USD","in_stock":true},{"title":"500 μg IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 106034 \/ Store at -20°C \/ 365days","offer_id":57280522682746,"sku":"106034","price":2084.38,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/es\/products\/recombinant-mouse-il-12-beta-protein-his-tag","provider":"xfnano","version":"1.0","type":"link"}