Water soluble oxidized chitosan

Product Name Water soluble oxidized chitosan Product Overview Chitosan (CS) is a natural biopolymer synthesized by deacetylating chitin. It has low solubility in water, but can dissolve in weak acids to form a viscous colloidal solution. Chitosan is a type of amino polysaccharide that can be chemically modified with active functional groups to obtain many chemical substances. There are two active functional groups on its molecular chain, - NH2 and - OH, with - NH2 being more active than - OH. Modifying these two functional groups can form compounds with different structures and properties, expanding the application fields of chitosan. Oxidized chitosan (OCS) is generally one of the most important modified derivatives of chitosan, which is selectively oxidized by sodium periodate to break the sugar unit C2-C3 structure and generate active aldehyde groups. Technical Parameter Diameter:White sponge like solid Product Features 1) Highly reactive crosslinking sites: Aldehyde groups (- CHO) can rapidly react with substances containing amino groups (- NH ₂) (such as chitosan itself, proteins, etc.) to form dynamic Schiff base bonds (- C=N -). This reaction is the basis for many applications of aldehyde functionalized chitosan. 2) Excellent solubility: The introduction of aldehyde groups disrupts the original lattice structure of chitosan, significantly improving its solubility in neutral aqueous solutions. 3) Good biocompatibility and modifiability: Despite chemical modification, OCS still retains good biocompatibility and low immunogenicity. In addition, aldehyde groups serve as a "handle" that can easily couple various functional molecules, such as targeting peptides, growth factors, antibiotics, or fluorescent probes, to prepare functionalized smart materials. Application Fields 1) Drug loaded hydrogel: The in-situ hydrogel formed by OCS and amino containing polymer can be used as a drug repository to achieve local and continuous drug release, and can be used to treat local diseases (such as arthritis, eye diseases) or postoperative anti adhesion. 2) Biomedical materials: used to prepare hydrogels and wound dressings from collagen, gelatin and silk fibroin, replace toxic crosslinking agents such as glutaraldehyde, and prepare medical dressings for hemostasis and healing promotion; Aldehyde groups covalently bind with histone amino groups, resulting in good adhesion. 3) Environmental water treatment: Aldehyde groups, carboxyl groups, and amino groups on molecules provide a large number of adsorption sites for adsorbing heavy metal ions and organic dye wastewater; Can be used as a flocculant to treat wastewater, easily degradable, and has minimal secondary pollution.