{"product_id":"hyaluronic-acid-oxide","title":"Hyaluronic acid oxide","description":"\u003cp\u003eProduct Name Name: Hyaluronic acid oxide Product Overview XFBM1334 is a biomedical-grade oxidized hyaluronic acid offered by XFNANO. Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan composed of repeating disaccharide units of D-glucuronic acid and N-acetyl-D-glucosamine. As a major component of the extracellular matrix, HA exhibits outstanding moisture retention and biocompatibility, and plays key roles in cell proliferation, differentiation, morphogenesis, inflammation and wound healing. XFBM1334 is produced by selective sodium-periodate (NaIO₄) oxidation that cleaves the C2–C3 vicinal diol of the glucuronic-acid residues and introduces highly reactive aldehyde groups (-CHO). These aldehydes react with amino (-NH₂) or hydrazide (-NHNH₂) bearing molecules — such as carboxymethyl chitosan (CMCS), gelatin or hydrazide-modified HA — via Schiff-base chemistry under mild physiological conditions, forming dynamic imine bonds to build injectable, self-healing hydrogels in situ without UV, heat or toxic crosslinkers, with broad prospects in drug delivery, wound dressing and tissue engineering. Technical Parameter Repeating Unit D-glucuronic acid + N-acetyl-D-glucosamine disaccharide Mechanism NaIO₄ : NaIO₄ periodate oxidation of C2–C3 vicinal diols → dialdehyde ring-opening Degree of Oxidation: 20–40 % (determined by ¹H NMR integration) Molecular Weight : Derived from 150,000–250,000 Da HA; other MW grades available on request Appearance: White spongy lyophilized solid Solubility : Soluble in water and PBS (clear viscous solution) Product Features Antioxidant: Selenium is an essential trace element for organisms and animals. It plays a very important role in antioxidant and maintaining redox homeostasis in various metabolic processes. Selenium nanoparticles can be better absorbed and utilized by the body, thereby performing their antioxidant function more effectively. Antibacterial properties: Selenium nanoparticles have great potential as broad-spectrum antibacterial agents and have important antibacterial activity against pathogenic bacteria, fungi and parasites. Its small diameter and large contact area with the bacterial cell membrane can directly destroy the bacterial cell membrane and cause its death. Anti-tumor properties: Selenium nanoparticles can regulate the redox state within cells and inhibit tumor cell proliferation, migration and invasion. Its anti-tumor effect is achieved by inhibiting the regulation of cell cycle replication, reducing and increasing apoptosis, and inhibiting NF-KB and p53 signaling pathways. Enhance immunity: Selenium nanoparticles can enhance the body's immune function, including the activity of natural killer cells, the activity of T cells and the secretion of white blood cells. By enhancing the body's immunity, the proliferation and spread of tumor cells can be prevented. Stability and solubility: Selenium nanoparticles have the characteristics of large surface area, good solubility, and high stability, which make them have potential application prospects in biological and other fields. Application Fields Medical applications: Selenium nanoparticles have broad application prospects in the medical field, such as as an adjuvant for cancer treatment drugs or for the treatment of viral infections. Food preservation: Selenium nanoparticles can be used to preserve food such as meat, seafood, fruits and vegetables, and can extend the shelf life of food. Cosmetics: Selenium nanoparticles can improve skin condition and have antioxidant, moisturizing, anti-wrinkle and other effects, so they can be used in cosmetics. Environmental management: Selenium nanoparticles can be used in water treatment to remove heavy metals, chemicals and other harmful substances in water. Related Information Please e-mail for the detailed characterization data. E-mail:sales@xfnano.com\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"1g OX20%-40% 110664 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280553124218,"sku":"110664","price":242.19,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/fr\/products\/hyaluronic-acid-oxide","provider":"xfnano","version":"1.0","type":"link"}