{"product_id":"recombinant-human-il-12-beta-protein-his-tag","title":"Recombinant Human IL-12 beta Protein (His-tag)","description":"\u003cp\u003eDESCRIPTION Synonym IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 Species Human Accession P29460 Source HEK293 cells SPECIFICATIONS Amino acid sequence Ile23-Ser328 is expressed with a 10×His tag at the C terminus Molecular Weight 36.1 kDa Purity \u0026gt;95.0% as determined by SDS-PAGE Endotoxin \u0026lt;5 EU·mg-1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND Subunit beta of interleukin 12 (IL12B) is a subunit of human interleukin 12. Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK\/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B\/IL-12B is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine is important for sustaining a sufficient number of memory\/effector Th1 cells to mediate long-term protection to an intracellular pathogen. IL12B Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. Data SDS-PAGE Bioactivity Active Recombinant Human IL-12 beta Protein was determined by SDS-PAGE with Coomassie Blue.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 μg IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 106026 \/ Store at -20°C \/ 365days","offer_id":57280522420602,"sku":"106026","price":90.63,"currency_code":"USD","in_stock":true},{"title":"100 μg IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 106027 \/ Store at -20°C \/ 365days","offer_id":57280522453370,"sku":"106027","price":506.25,"currency_code":"USD","in_stock":true},{"title":"500 μg IL12B,p40,CLMF,CLMF2,NKSF,NKSF2 106028 \/ Store at -20°C \/ 365days","offer_id":57280522486138,"sku":"106028","price":1935.94,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/fr\/products\/recombinant-human-il-12-beta-protein-his-tag","provider":"xfnano","version":"1.0","type":"link"}