{"product_id":"recombinant-human-il-4-protein","title":"Recombinant Human IL-4 Protein","description":"\u003cp\u003eDESCRIPTION Gene Name Synonym IL-4, IL4, BCGF1, BSF1 Species Human Accession P05112 Source HEK293 cells SPECIFICATIONS Amino acid sequence His25-Ser153 Molecular Weight 15 kDa Purity \u0026gt;95.0% as determined by SDS-PAGE Endotoxin \u0026lt;5 EU mg-1 Formulation Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 \/ IL-13 family. IL-4 was first identified as a T cell-derived growth factor for B cells. In addition to T cells, IL-4 is produced by innate lymphocytes, such as NTK cells, and myeloid cells, such as basophils and mast cells. Interleukin-4 \/ IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. Interleukin-4 \/ IL4 also regulates the expression of the low-affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Interleukin-4 is essential for the switching of B cells to IgE antibody production and the maturation of T helper (Th) cells toward the Th2 phenotype. It participates in at least several B-cell activation processes as well as other cell types. Data SDS-PAGE Bioactivity Active Recombinant Human IL-4 Protein was determined by SDS-PAGE with Coomassie Blue.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 μg IL-4, IL4, BCGF1, BSF1 106071 \/ Store at -20°C \/ 365days","offer_id":57280525074810,"sku":"106071","price":87.5,"currency_code":"USD","in_stock":true},{"title":"100 μg IL-4, IL4, BCGF1, BSF1 106072 \/ Store at -20°C \/ 365days","offer_id":57280525107578,"sku":"106072","price":446.88,"currency_code":"USD","in_stock":true},{"title":"500 μg IL-4, IL4, BCGF1, BSF1 106073 \/ Store at -20°C \/ 365days","offer_id":57280525140346,"sku":"106073","price":1637.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/fr\/products\/recombinant-human-il-4-protein","provider":"xfnano","version":"1.0","type":"link"}