{"product_id":"recombinant-mouse-bdnf-protein-his-tag","title":"Recombinant Mouse BDNF Protein (His-tag)","description":"\u003cp\u003eDESCRIPTION Gene Name Synonym Brain-derived Neurotrophic Factor Species Mouse Accession P21237 Source HEK293 cells SPECIFICATIONS Amino acid sequence Ala19-Arg249 is expressed with a 10×His tag at the C terminus Molecular Weight 27.5 kDa Purity \u0026gt;95.0% as determined by SDS-PAGE Endotoxin \u0026lt;5 EU·mg-1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND Brain-derived neurotrophic factor (BDNF) is a well-studied growth factor that serves many critical functions within the central nervous system (CNS). BDNF has a role in processes such as neuronal maturation, synapse formation and synaptic plasticity among others in the brain.BDNF is a member of the neurotrophin family that includes nerve growth factor (NGF), neurotrophin-3 (NT3), and neutorophin-4 (NT4). BDNF is widely expressed in the CNS and can exert profound effects on development, morphology, and synaptic plasticity and function in the brain. Data SDS-PAGE Bioactivity Recombinant Mouse BDNF Protein was determined by SDS-PAGE with Coomassie Blue. Measured in a cell proliferation assay using C6 cells. The ED50 for this effect is 0.1-1 µg\/mL.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 μg Brain-derived Neurotrophic Factor 106217 \/ Store at -20°C \/ 365days","offer_id":57280527532410,"sku":"106217","price":170.31,"currency_code":"USD","in_stock":true},{"title":"100 μg Brain-derived Neurotrophic Factor 106218 \/ Store at -20°C \/ 365days","offer_id":57280527565178,"sku":"106218","price":1139.06,"currency_code":"USD","in_stock":true},{"title":"500 μg Brain-derived Neurotrophic Factor 106219 \/ Store at -20°C \/ 365days","offer_id":57280527597946,"sku":"106219","price":3178.13,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/fr\/products\/recombinant-mouse-bdnf-protein-his-tag","provider":"xfnano","version":"1.0","type":"link"}