{"product_id":"recombinant-mouse-ifn-gamma-protein-his-tag","title":"Recombinant Mouse IFN-gamma Protein (His-tag)","description":"\u003cp\u003eDESCRIPTION Gene Name Synonym IFN-gamma, IFNγ, Interferon-gamma, Interferon-γ Species Mouse Accession P01580 Source HEK293 cells SPECIFICATIONS Amino acid sequence His23-Cys155 is expressed with a 10×His tag at the C terminus Molecular Weight 16.9 kDa Purity \u0026gt;95.0% as determined by SDS-PAGE Endotoxin \u0026lt;5 EU mg-1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. Interferon (IFN)-γ is the uppermost cytokine implicated in anti-tumor immunity. With its cytostatic, pro-apoptotic and immune-provoking effects, IFN-γ plays a central role in the recognition and elimination of transformed cells. Interferon-γ (IFN-γ) also plays a key role in activation of cellular immunity and subsequently, stimulation of antitumor immune-response.IFN-γ is considered potentially useful for adjuvant immunotherapy for different types of cancer.IFN-γ is considered potentially useful for adjuvant immunotherapy for different types of cancer. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. Data SDS-PAGE Bioactivity Recombinant Mouse IFN-gamma Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 18-30 kDa. Determined by its ability to induce STAT1\/STAT2 activation in B16 F1 ISRE LUC reporter cells.The ED50 for this effect is 5-10 ng\/mL.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 μg IFN-gamma, IFNγ, Interferon-gamma, Interferon-γ 106357 \/ Store at -20°C \/ 365days","offer_id":57280529138042,"sku":"106357","price":85.94,"currency_code":"USD","in_stock":true},{"title":"100 μg IFN-gamma, IFNγ, Interferon-gamma, Interferon-γ 106358 \/ Store at -20°C \/ 365days","offer_id":57280529170810,"sku":"106358","price":570.31,"currency_code":"USD","in_stock":true},{"title":"500 μg IFN-gamma, IFNγ, Interferon-gamma, Interferon-γ 106359 \/ Store at -20°C \/ 365days","offer_id":57280529203578,"sku":"106359","price":1589.06,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/fr\/products\/recombinant-mouse-ifn-gamma-protein-his-tag","provider":"xfnano","version":"1.0","type":"link"}