{"product_id":"recombinant-mouse-il-13-protein-his-tag","title":"Recombinant Mouse IL-13 Protein (His-tag)","description":"\u003cp\u003eDESCRIPTION Gene Name Synonym IL-13, IL13, NC30, ALRH, BHR1, MGC116786, MGC116788, MGC116789, P600, Interleukin-13 Species Mouse Accession P20109 Source CHO Cells SPECIFICATIONS Amino acid sequence Ala19-Phe131 is expressed with a 10×His tag at the C terminus Molecular Weight 13.8 kDa Purity \u0026gt;95.0% as determined by SDS-PAGE Endotoxin \u0026lt;5 EU·mg-1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13\/IL-4 family. Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. IL-13, a T-helper type 2 (Th2) cytokine, was first described in 1993, identified by molecular cloning in activated human T lymphocytes. IL-13 was reported to direct cells towards the Th2 pathway, with induction of B cell production of IgE. As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. In particular, IL-13 up-regulation is associated with severe disease. Data SDS-PAGE Bioactivity Active Recombinant Mouse IL-13 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 18-30 kDa. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 1-10 ng\/mL.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 μg IL-13, IL13 106062 \/ Store at -20°C \/ 365days","offer_id":57280523960698,"sku":"106062","price":179.69,"currency_code":"USD","in_stock":true},{"title":"100 μg IL-13, IL13 106063 \/ Store at -20°C \/ 365days","offer_id":57280523993466,"sku":"106063","price":1340.63,"currency_code":"USD","in_stock":true},{"title":"500 μg IL-13, IL13 106064 \/ Store at -20°C \/ 365days","offer_id":57280524026234,"sku":"106064","price":3571.88,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/fr\/products\/recombinant-mouse-il-13-protein-his-tag","provider":"xfnano","version":"1.0","type":"link"}