{"product_id":"polylactic-acid","title":"Polylactic Acid","description":"\u003cp\u003eProduct Name Polylactic Acid Product Overview Polylactic Acid (PLA) microspheres are classic bio-based degradable polymer micro-nano materials polymerized from lactic acid extracted from renewable plant resources. They have excellent biocompatibility, high-strength mechanical properties and controllable biodegradability, and are the most widely used core consumables in the fields of biomedicine, tissue engineering, drug sustained release and environmental material scientific research. This series of scientific research-grade monodisperse PLA microspheres covers a full gradient range of nano and submicron particle sizes from 50 nm to 1.0 μm, with a uniform solid content of 1% and a single bottle volume of 10 ml. Prepared by high-precision emulsion polymerization and multi-stage classification purification technology, the products feature full sphericity, uniform particle size, no agglomeration, no irregular particles, and excellent batch stability and experimental repeatability. Certified by ISO 10993 biocompatibility standard, PLA materials can be completely degraded in organisms and natural environments, finally metabolized into carbon dioxide and water without toxicity or residue. Compared with flexible PCL materials, PLA microspheres have higher rigidity, excellent mechanical stability and moderate degradation rate, with an in-vivo degradation cycle of about 6~12 months, suitable for medium and short-term drug sustained release and hard tissue repair scenarios. With stable original performance, the products support full-type surface functional group modification and large particle size customization to meet differentiated cutting-edge scientific research needs. Technical Parameter Dispersion Solvent:Sterile Deionized Water Solid Content 2.5% Surface Modification :Unmodified; Support customized modification of various functional groups such as amino, carboxyl and biotin Surface Charge :Original weak negative charge with stable properties, accurately adjustable by surface modification Color :Milky white uniform suspension dispersion Storage Condition:Store at 2~8°C away from light, sealed and refrigerated. Do not freeze-thaw, store at high temperatures, or expose to room temperature for extended periods Shelf Life 12months(Under standardized unopened refrigerated storage conditions) Product Features •Green Bio-based Material with Complete Safe Degradation: Derived from renewable plant raw materials such as corn and straw, PLA is a pure natural bio-based polymer material without chemical toxin residues. It can be completely degraded into harmless small molecules in natural environments and organisms without environmental pollution or biological toxicity, complying with green material research standards and suitable for various environmental protection and biomedical scenarios. •Excellent Rigid Mechanics and Strong Structural Stability: Compared with flexible PCL microspheres, PLA microspheres have higher rigidity, excellent mechanical strength, strong deformation resistance and good high-temperature stability. They are not easy to break or deform during experiments, adapting to harsh experimental scenarios such as hard tissue repair, high-strength scaffold preparation and material mechanical modification. •Controllable Degradation Rate for Medium and Short-term Sustained Release: The in-vivo and in-vitro degradation cycle is stably 6~12 months with moderate and controllable degradation rate, which accurately meets the experimental needs of medium and short-term drug sustained release, wound repair and temporary tissue support, avoiding the problems of rapid degradation failure and long-term degradation residue. •Ultra-high Monodispersity and Excellent Experimental Repeatability: Adopting multi-stage precise classification technology, all series have uniform and regular particle sizes, full sphericity and no agglomeration. With PDI ≤ 0.3 and excellent batch consistency, it effectively ensures accurate, stable and repeatable data of drug encapsulation rate, adsorption experiments and cell experiments. •Medical-grade Biocompatibility with Wide Application Scenarios: Certified by ISO 10993 biosafety standard, it has no sensitization, no cytotoxicity and no immune rejection, suitable for high-end biological research fields such as in-vivo animal experiments, implantable material R\u0026amp;D and medical consumable modification. •Full-dimensional Customization and Outstanding Cost Performance: It covers the full particle size gradient from nanometer to 200 μm, supports multiple types of surface functional modification with strong parameter adjustability. All series adopt standardized mass production and transparent pricing with stable quality, featuring higher customization flexibility and more significant cost performance advantages than similar biodegradable microspheres. Application Fields •Medium and Short-term Sustained Drug Delivery: Relying on moderate and controllable degradation cycle and excellent encapsulation performance, it can efficiently load active substances such as small-molecule drugs, proteins, polypeptides and vaccine antigens to achieve months-level uniform sustained release, stabilize drug concentration and optimize administration cycle, suitable for the R\u0026amp;D experiments of anti-inflammatory, anti-tumor and vaccine sustained-release preparations. •Hard Tissue Engineering and Regenerative Medicine: With high rigid mechanical properties, it can be used as repair scaffolds and cell culture carriers for hard tissues such as bone and cartilage, adapting to scenarios such as bone defect repair, orthopedic implant material modification and hard tissue regeneration mechanism research, providing stable mechanical support for hard tissue repair. •Biological Detection and Labeling Imaging: Modified with functional groups or fluorescence, it can be used for biomolecular coupling, specific cell labeling, in-vitro immune detection and in-vivo fluorescence imaging experiments with low background interference and stable signals, suitable for high-precision biosensing and diagnostic scientific research. Green Degradable Material R\u0026amp;D: As a typical bio-based degradable model material, it is widely used in the modified R\u0026amp;D of degradable plastics, environmental protection coatings and disposable •medical consumables. It researches material degradation mechanism, environmental adaptability and microplastic alternative schemes to promote the iterative upgrading of green polymer materials. •Wound Repair and Medical Dressing R\u0026amp;D: It can load antibacterial and repair factors to prepare functional sustained-release dressings, realizing long-term bacteriostasis and uniform repair of wounds, suitable for scientific research experiments on skin wound and chronic wound repair materials. •Basic Colloid and Interface Scientific Research: PLA microspheres with complete monodisperse size gradient can be used in basic theoretical research such as colloid assembly, emulsion stabilization, particle interface adsorption and nano-dispersion system, with excellent experimental data stability and repeatability. User Guide 1. All products of this series are scientific research-grade consumables, only for laboratory scientific research, not for medical injection or industrial end products, and are prohibited from direct human clinical injection and treatment. 2. The products need to be sealed and refrigerated at 2~8°C away from light. Freezing, high-temperature exposure, long-term storage at room temperature and repeated freeze-thaw are strictly prohibited. It is recommended to use up within 1 month after opening to prevent microsphere sedimentation, agglomeration and dispersion failure. 3. All series support customized modification of surface functional groups. The quotation and customization cycle vary with different modification processes. Please consult customer service in advance to confirm specific parameters and schemes before ordering. 4. The parameters in this specification are general standard values. Minor physical deviations between batches are within the industry allowable error range and will not affect conventional scientific research experiments. 5. PCL material has long-term degradable characteristics. Long-term exposure to high temperature, strong acid, alkali and strong organic solvent environments should be avoided to prevent premature degradation and structural damage of microspheres and ensure experimental validity.strictly prohibited. It is recommended to use up within 1 month after opening to prevent microsphere sedimentation, agglomeration and dispersion failure. 3. All series support large particle size customization of 1μm~200μm and various surface functional group modifications. The quotation and production cycle vary with different customization schemes. Please consult customer service to confirm detailed parameters and schemes before ordering. 4. The parameters in this specification are general standard values. Minor physical deviations between batches are within the industry allowable error range and will not affect conventional scientific research experiments. 5. PLA materials are degradable. Long-term exposure to high temperature, strong acid, alkali and strong organic solvent environments should be avoided to prevent premature degradation and structural damage of microspheres and ensure experimental validity.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10mL 50nm,1% 111121 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573505914,"sku":"111121","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 80nm,1% 111122 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573538682,"sku":"111122","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 100nm,1% 111123 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573571450,"sku":"111123","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 200nm,1% 111124 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573604218,"sku":"111124","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 300nm,1% 111125 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573636986,"sku":"111125","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 400nm,1% 111126 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573669754,"sku":"111126","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 500nm,1% 111127 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573702522,"sku":"111127","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 600nm,1% 111128 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573735290,"sku":"111128","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 700nm,1% 111129 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573768058,"sku":"111129","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 800nm,1% 111130 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573800826,"sku":"111130","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 900nm,1% 111131 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573833594,"sku":"111131","price":157.81,"currency_code":"USD","in_stock":true},{"title":"10mL 1μm,1% 111132 \/ Store at 4°C refrigerated \/ 365days","offer_id":57280573866362,"sku":"111132","price":157.81,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/products\/polylactic-acid","provider":"xfnano","version":"1.0","type":"link"}