{"product_id":"recombinant-rat-il-10-protein-his-tag","title":"Recombinant Rat IL-10 Protein (His-tag)","description":"\u003cp\u003eDESCRIPTION Gene Name Synonym IL-10, Il10, Il-10 Species Rat Accession P29456 Source HEK293 cells SPECIFICATIONS Amino acid sequence Met19-Asn178 is expressed with a 6×His tag at the C terminus Molecular Weight 21.6 kDa Purity \u0026gt;95.0% as determined by SDS-PAGE Endotoxin \u0026lt;5 EU mg-1 Formulation Lyophilized from sterile PBS, pH 7.4.Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Reconstitution Dissolved in sterile water, it is recommended to add 0.1% HSA or BSA for long-term preservation. STORAGE Stability and Storage 12 months from date of receipt at -20°C to -70°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for almost 6 months (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage. BACKGROUND Interleukin-10 (IL-10) is an anti-inflammatory cytokine that belongs to the IL-10 family.The Interleukin (IL)-10 cytokine family includes IL-10, IL-19, IL-20, IL-22, IL-24, and IL-26, which are considered as Class 2α-helical cytokines. IL-10, a cytokine with anti-inflammatory properties, has a central role in infection by limiting the immune response to pathogens and thereby preventing damage to the host. IL10 is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by monocytes and to a lesser extent by lymphocytes. Data SDS-PAGE Bioactivity Active Recombinant Rat IL-10 Protein was determined by SDS-PAGE with Coomassie Blue. Measured in a cell proliferation assay using MC\/9 mouse mast cells. The ED50 for this effect is 3-8 ng\/mL.\u003c\/p\u003e","brand":"xfnano","offers":[{"title":"10 μg IL-10, Il10, Il-10 106020 \/ Store at -20°C \/ 365days","offer_id":57280522223994,"sku":"106020","price":246.88,"currency_code":"USD","in_stock":true},{"title":"100 μg IL-10, Il10, Il-10 106021 \/ Store at -20°C \/ 365days","offer_id":57280522256762,"sku":"106021","price":1614.06,"currency_code":"USD","in_stock":true},{"title":"500 μg IL-10, Il10, Il-10 106022 \/ Store at -20°C \/ 365days","offer_id":57280522289530,"sku":"106022","price":4360.94,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0907\/3606\/6938\/files\/1_27871cef-ce01-415a-9a0e-d29d5e516d17.png?v=1780024497","url":"https:\/\/chinanano.com\/products\/recombinant-rat-il-10-protein-his-tag","provider":"xfnano","version":"1.0","type":"link"}