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Biotin modified magnetic beads

$314.29
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Product Name

Name: Biotin modified magnetic beads

Product Overview

Biotin modified magnetic beads are a special type of magnetic bead product that covalently couples Biotin to superparamagnetic nanoscale magnetic beads, enabling rapid, efficient, sensitive, and specific binding with Streptavidin or Avidin, as well as antibodies, nucleic acids, proteins, and other molecules conjugated with these molecules. This type of magnetic bead is widely used for the separation and purification of nucleic acids, antibodies, proteins, or related complexes conjugated with avidin or streptavidin, for immunoprecipitation (IP), cell sorting, DNA protein interaction research, etc.

Product Features

High binding capacity, providing rapid separation and purification capabilities.

Strong specificity, capable of specifically binding to molecules coupled with streptavidin.

The bonding speed is fast, with a large specific surface area, effectively reducing the time required for bonding.

Application Fields

Biomedical research: In proteomics, it is used for protein separation, purification, and enrichment to improve protein yield and purity. In genomics, they facilitate the separation and enrichment of gene fragments, providing raw materials for subsequent gene analysis and editing. In addition, they also play a role in immune analysis by specifically capturing and isolating target biomolecules.

Biotechnology: Biotin modified magnetic beads are used as drug carriers to target drug molecules to the lesion site, improving therapeutic efficacy and reducing side effects. They are also used to construct biosensors based on the biotin streptavidin system for detecting biomolecules, ions, and cells.

Molecular Biology: Magnetic beads are widely used in various fields of molecular biology, such as second-generation sequencing (NGS), polymerase chain reaction (PCR), quantitative PCR (qPCR), droplet digital PCR (ddPCR), and other amplification and genotyping applications, as well as protein purification.

Nucleic acid extraction: The method of purifying nucleic acids using magnetic beads began in the 1990s. This method allows for reversible binding of nucleic acids using coated magnetic beads by simply adjusting the buffer conditions.

Protein purification: In the field of protein purification, biological magnetic beads guide the specific binding of magnetic beads to proteins under a magnetic field, achieving high-energy efficiency separation of proteins.

Chemiluminescence and Biosensing: In the field of chemiluminescence, bio magnetic beads can be used as carriers for fluorescence labeling and detection, improving the sensitivity and specificity of detection.

Cell sorting: In cytological research, biological magnetic beads are used for cell sorting and separation, achieving high-energy extraction of specific cell subpopulations.

Related Information

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