Product Name
Name:a>PEI coated Fe3O4 nanoparticles
Product Overview
Magnetic Fe3O4 nanoparticles modified with polyethyleneimine (PEI) are a composite nanomaterial that combines the characteristics of magnetic nanoparticles and polyethyleneimine. Polyethyleneimine is a highly branched polymer with a high density of amino groups. These amino groups can stabilize Fe3O4 nanoparticles and provide further functional modification sites. The amino group of PEI endows Fe3O4 nanoparticles with a higher surface positive charge, which helps to enhance the interaction with negatively charged cell membranes.
Technical Parameter
Color:Brown dispersion
Particle size: 10nm:0nm:0nm:0nm:0nm:0nm:00nm (Size can be customized)
Main ingredient:PEI@Fe3O4、Water
Fe potency:1mg/mL
Product Features
High surface charge: The high-density amino groups of PEI molecules endow Fe3O4 nanoparticles with a high surface positive charge, which helps to improve their stability and phagocytic efficiency in vivo.
Good colloidal stability: PEI modification enhances the dispersibility of Fe3O4 nanoparticles in aqueous media, preventing particle aggregation.
Magnetic resonance imaging contrast enhancement: In MRI, these nanoparticles can serve as contrast agents to enhance the contrast of imaging.
Easy to be engulfed by cells: Due to their surface properties, these nanoparticles are easily engulfed by cells, which helps achieve intracellular delivery of drugs.
Can be used for transfection research: The transfection ability of PEI makes its modified Fe3O4 nanoparticles suitable for cell transfection experiments of DNA or RNA.
Application Fields
Magnetic Resonance Imaging (MRI): PEI modified Fe3O4 nanoparticles can serve as negative contrast agents for MRI, enhancing imaging contrast and improving disease detection sensitivity.
Targeted molecular imaging: By modifying the surface of Fe3O4 nanoparticles with targeted molecules such as fluorescein isothiocyanate (FITC), folate (FA), or hyaluronic acid (HA), the imaging specificity for specific cells or tissues can be improved.
Dual modal or multimodal imaging: By combining PEI modified Fe3O4 nanoparticles with other imaging materials such as gold (Au) nanoparticles, composite nanoparticles can be developed for MR/CT (computed tomography) dual-mode imaging.
Drug delivery system: PEI's high-density amino groups can form stable complexes with drug molecules, utilizing the magnetic properties of Fe3O4 nanoparticles to achieve targeted delivery and controlled release of drugs.
Related Information
Please e-mail for the detailed characterization data.
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