Product Name
Fe3O4@SiO2 nanoparticle
Product Overview
Silica-coated magnetic nanoparticles are a composite material consisting of a core of the magnetic material tri-iron tetraoxide (Fe3O4) and a shell of silicon dioxide (SiO2). The silica-coated magnetic nanoparticles are biocompatible and protect the biological activity of biological enzymes, DNA, and other biologically active substances, and can be used as a carrier for the controlled release of these substances to enable targeted therapy of drugs. Due to their many unique physical and chemical properties, core-shell structured nanomaterials have potential applications in superhydrophobic surface coatings, chemistry, magnetism, electricity, optics, biomedicine and other fields. In addition to this, CDF can also provide core-shell structures such as magnetic iron tetraoxide encapsulated in mesoporous silicon, gold-in-silicon, silver-in-silicon, gold-in-magnetism, and gold-in-silver.
Technical Parameter
Inner core diameter:-15nm
Particle diameter:0-20 nm
Appearance：Brown powder
Concentration:1-10 mg/ml
Solvent：ETOH
Product Features
Biocompatibility: The silica shell provides good biocompatibility, reducing the potential toxicity of the particles to the organism.
Stability: The silica shell protects the inner core from oxidation and corrosion, increasing the stability of the particles in the organism.
Easy functionalisation: the abundance of silica hydroxyl groups (Si-OH) on the surface of silica provides easy surface modification of the particles, which can be chemically linked to drugs, fluorescent markers, targeting ligands, etc.
Good dispersibility: the silica shell helps to improve the dispersibility of the particles in aqueous and organic solvents and reduce agglomeration.
Multifunctionality: different functional molecules can be combined to achieve a variety of biomedical functions, such as drug delivery, imaging, and therapy.
Application Fields
Targeted drug delivery: the silicon-coated magnetic nanoparticles can be used as a drug carrier, through the positioning of the external magnetic field, the drug will be delivered directly to the lesion site, to achieve targeted drug delivery, especially suitable for the diagnosis and treatment of specific types of cancer .
Magnetothermal therapy: Using the heat generated by the silicon-coated magnetic nanoparticles inside the tumour cells, the heat generated by the external magnetic field can kill the tumour cells, which is a method of treating cancer in addition to surgery, chemotherapy and radiotherapy.
Magnetic Resonance Imaging (MRI) contrast agent: Due to their superparamagnetic properties, Si-encapsulated magnetic nanoparticles can be used as contrast enhancers for MRI, improving the clarity and contrast of the image.
Separation and enrichment of biomolecules: Si-encapsulated magnetic nanoparticles can be used for rapid separation and enrichment of specific molecules in biological samples, such as in proteomics research.
Biosensing: The magnetic properties of Si-encapsulated magnetic nanoparticles allow the development of novel biosensors for the detection of biomolecular interactions.
Tissue engineering: Si-encapsulated magnetic nanoparticles can be used as bone tissue regeneration materials to promote osteogenic differentiation for tissue engineering research.
Related Information
Sealed, avoid light, and keep at 4¡ãC Expiry date: Six months.Please e-mail for the detailed characterizationdata.
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