Product Name
Name: Mesoporous silica（globular:/span>
Product Overview
Mesoporous materials (pore size 2-50nm) are between microporous materials (pore size <2 nm) and macroporous materials (pore size > 50nm). They have many excellent characteristics, such as highly ordered pore structure, single pore size distribution, and high stability, and have become a research hotspot in recent years.
As a common inorganic nanoparticle, silica nanoparticles have a series of advantages such as controllable morphology, orderly and adjustable pore structure, large specific surface area, easy modification of surface functional groups, and good biocompatibility, which make them widely used in biomedicine, catalysis, environmental protection, optics and other fields.
The main preparation method of silica nanoparticles is sol-gel method, and the silicon source is formed by hydrolysis polycondensation under catalysis. The method was first proposed by Stober in 1968. According to the morphology characteristics of silica nanoparticles, they can be roughly divided into three types: solid silica, mesoporous silica and hollow structure silica. Among them, the pore structure of mesoporous silica is generally formed by template method, and the template includes soft template and hard template. Soft templates are generally biparental surfactants, and hard templates are generally high molecular polymers, of which soft templates are more commonly used. The preparation process of mesoporous silicon can be divided into two stages: first, the template interacts with the inorganic precursor, and the liquid crystal phase with nanometer lattice constant of organic matter and inorganic matter is synthesized under certain conditions; Then the template is removed by high-temperature heat treatment or other physical and chemical methods, and the space left by the template constitutes the mesoporous pore channel.
The surface of silica nanoparticles is rich in silicon hydroxyl group, which is conducive to the chemical modification of the surface. By modifying different functional groups, silica nanoparticles can be given more functions. At present, the commonly used surface modification types are surface amination, sulfhydrylation, organic chain functionalization and so on. The surface modification of silica nanoparticles is mainly through the introduction of different types of silane coupling agents, such as 3-aminopropyl triethoxysilane (APTES), which can be used for amination modification, and 3-mercaptopropyl trimethoxysilane can be used for sulfhydryl modification.
Technical Parameter
Status:White powder
Product Features
1. High specific surface area: it can provide a large number of active sites, enhance the interaction with other substances, and load more catalysts in the catalytic reaction to improve the reaction efficiency.
2. Orderly mesoporous structure: the aperture size is uniform and adjustable, which is conducive to the transmission and diffusion of substances. In drug delivery, the release rate of drug molecules can be controlled.
3. Good thermal stability and chemical stability: can maintain the stability of structure and performance in high temperature and a variety of chemical environments
4. Strong surface modifiable: it is easy to functionalize its surface by chemical methods to meet different application needs.
5. Good biocompatibility: When applied in the biomedical field, it usually has low toxicity to organisms and high safety.
Application Fields
1. Drug delivery: anticancer drugs are loaded into mesoporous silica pores to achieve slow drug release. Through surface modification, the drug can target specific tumor cells, improving the therapeutic effect while reducing the damage to normal cells.
2. Biological imaging: Loaded with fluorescent molecules (FITC, Cy5.5) or magnetic nanoparticles, it is used for imaging cells and in vivo to achieve real-time monitoring of biological processes in cells.
3. Gene therapy: as a gene carrier, to protect the stability and transmission efficiency of genes in the body.
4. Diagnostic reagents: used to detect biomarkers, such as loading molecules that can specifically identify disease-related markers to achieve early diagnosis of diseases.
5. Tissue engineering: as a scaffold material, it promotes the growth of cells and the regeneration of tissues.
Related Information
Please e-mail for the detailed characterization data.
E-mail:sales@xfnano.com
){kind=link}