Carboxyl Modified Dendritic Large Pore Mesoporous Silica

Product Name

Carboxyl Modified Dendritic Large Pore Mesoporous Silica

Product Overview

Silica nanoparticles can be broadly classified into three types based on their morphological characteristics: solid silica, mesoporous silica and hollow-structured silica. Among them, the pore structure of mesoporous silica is generally formed by the template method. The preparation process of mesoporous silica can be divided into two stages: firstly, the template interacts with the inorganic precursor, and under certain conditions, the organic and inorganic substances are synthesized with nano-sized lattice constants of the liquid crystalline state of the structural phases; and then the template can be removed by using high-temperature heat treatment or other physicochemical methods, and the space left behind the template constitutes a mesoporous pore channel. Compared with conventional mesoporous silica, dendritic mesoporous silica has a dendritic pore structure with more complex and abundant connectivity between the pores, and the large pore size can also accommodate larger-sized molecules or particles, which has the advantages of high loading capacity and high utilisation rate.

Technical Parameter

Average size：~100 nm

Specific surface area:05.71m²/g

Average pore size：~13nm

Note: The BET data is a single measurement of a 100nm particle size product, allowing floating between different batches.    

Product Features

Unique pore structure: with a dendritic structure, this structure increases the internal pore connectivity and material transport channels. 

Larger pore size: able to accommodate guest molecules of larger size, such as macromolecular drugs, proteins, nanoparticles, etc., which provides a broader space for its application in biomedicine, catalysis and other fields. 

High porosity: provides a large specific surface area and pore volume, which is conducive to the adsorption and loading of a large number of substances. 

Good diffusion performance: dendritic pore channels and large pore size, substances can diffuse and transport rapidly in them. 

Loading and controlled release ability: it can achieve efficient loading of drugs and other substances, and can achieve precise controlled release of loaded substances by means of surface modification and other means to improve the therapeutic effect.

Application Fields

Drug delivery: loading of anti-cancer drugs such as Adriamycin into dendritic mesoporous silica. Due to its large pore size and good controlled release properties, the drug can be released slowly at the tumour site, improving the therapeutic effect while reducing the side effects on normal tissues. 

Gene Carrier: As a gene carrier, it protects genes from degradation by nucleases and delivers genes into cells. 

Catalysis: In multiphase catalysis, dendritic mesoporous silica can be used as a carrier to load metal nanoparticles or enzymes. For example, loaded platinum nanoparticles are used to catalyse hydrogenation reactions to improve reaction efficiency and selectivity. 

Sensors: Due to its adsorption ability on target molecules and changes in optical properties, it can be used to construct chemical sensors, such as detecting heavy metal ions or organic pollutants in the environment.

Related Information

Powder:Sealed, avoid light, and keep dry at room temperature, Expiry date: 1 year.

Liquid:Sealed, avoid light, and keep at 4¡ãC Expiry date:Six months.

Please e-mail for the detailed characterization data.

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