Circular Dichroism Test (CD)

Product Name Circular Dichroism Test (CD) Product Overview English Introduction: Circular Dichroism (CD) spectroscopy is a core spectral detection technology for characterizing the stereostructure, molecular conformation, optical activity, chiral purity and intermolecular interaction of chiral compounds. It is widely used in cutting-edge research fields such as biological macromolecules, organic chiral compounds, polypeptides and proteins, nucleic acids, chiral drugs and supramolecular assembly materials. Based on the difference in absorption coefficients of left and right circularly polarized light in chiral media, CD spectroscopy generates characteristic signals, which can accurately analyze the secondary structure of proteins, absolute configuration of chiral molecules, conformational stability, folding behavior and dynamic structural changes. It is an essential test method for the mechanism research of chiral materials, drug configuration analysis and structural characterization of biological macromolecules. Equipped with Japan JASCO J-1500 high-precision circular dichroism spectrometer, this testing service features strong optical stability, low baseline noise and high scanning accuracy, suitable for standardized testing of liquid samples. Accurate full-band scanning detection can be completed with only 0.2-5mL liquid samples. The test data complies with domestic and foreign general detection standards with high spectrum signal-to-noise ratio and excellent repeatability, and can be directly used for SCI paper publication, chiral mechanism demonstration, drug configuration calibration, biological structure analysis and scientific research project conclusion reports. Technical Parameter English Parameters: Instrument Model: Japan JASCO J-1500 circular dichroism spectrometer, an imported scientific research-grade chiral spectrum detection equipment and a global mainstream benchmark instrument for structural characterization of biological macromolecules and chiral compounds with high data recognition and strong industry universality Test Principle: Based on the differential absorption principle of left and right circularly polarized light, the high-precision optical system collects characteristic CD signals of chiral samples, which accurately reflect the asymmetric molecular structure and optical activity characteristics Scanning Performance: Equipped with a high-precision spectral scanning system, the scanning band covers the characteristic interval of conventional chiral structures, with uniform and controllable scanning speed, high spectrum resolution and complete signal details Optical Stability: The equipment is built with a precision optical path calibration system with extremely low baseline drift and small noise signals, which effectively avoids the interference of slight environmental fluctuations on spectral signals and ensures spectrum quality Signal Sensitivity: Ultra-high optical detection sensitivity can accurately capture the characteristic response of low-concentration samples and weak chiral signals, and effectively distinguish subtle molecular conformational changes and chiral differences Sample Adaptability: Specially adapted for liquid solution samples, suitable for aqueous solutions, buffer solutions and conventional organic solvent systems. High-precision spectrum collection can be completed with only 0.2-5mL trace liquid Data Functions: It can complete protein secondary structure fitting, chiral configuration judgment, conformational stability analysis and dynamic spectrum collection, and analyze sample chiral structure information in multiple dimensions Data Output: Outputs complete original CD spectrum, absorbance data, ellipticity parameters and original test files, which can be directly used for thesis drawing, structural fitting and chiral mechanism analysis Calibration System: The equipment undergoes regular optical path calibration, baseline calibration and standard sample calibration, with traceable data and excellent repeatability, meeting the data standards of high-end scientific research journals Product Features Original Japanese imported equipment with authoritative and universal data: Adopts JASCO J-1500 high-end scientific research-grade circular dichroism spectrometer, a universal standard equipment in the field of chiral scientific research at home and abroad. The spectrum quality and data accuracy meet the requirements of SCI journal publication, and can be directly used for papers, patents, project conclusions and authoritative test reports. Ultra-high sensitivity detection for weak chiral signals: The precise optical path combined with a low-noise detection system can accurately identify the characteristic signals of weak chiral and low-concentration samples, which is perfectly suitable for scientific research on fine conformational changes and subtle chiral differences. Trace liquid sample requirement with high sample utilization: A full set of scanning tests can be completed with only 0.2-5mL liquid samples without complex pretreatment, suitable for the detection of precious biological samples, high-value chiral drugs and trace synthetic samples. Excellent spectrum quality and high signal-to-noise ratio: The equipment has stable baseline and strong anti-interference ability. The output spectrum is smooth without miscellaneous peaks and has high signal recognition, which can be directly used for original thesis image display and data fitting analysis without secondary image modification. Multi-functional data analysis with high scientific research value: A single test can obtain complete chiral spectral information, supporting secondary structure fitting, configuration judgment and stability analysis, fully supporting chiral mechanism analysis and material structure optimization. Good data repeatability and outstanding stability: Standardized optical path calibration and scanning procedures ensure high coincidence of parallel test spectra and minimal data deviation. The experimental results are repeatable, traceable and comparable. Standardized service cycle with high cost performance: Transparent charging without hidden consumption and stable delivery within 5-7 working days, suitable for batch sample screening, control experiments and regular structural characterization of chiral materials. Application Fields Biomacromolecule Research Field: Secondary structure characterization of proteins, polypeptides, nucleic acids and enzyme preparations, analyzing the influence of temperature, pH and solvent environment on the conformational folding and structural stability of biomolecules. Chiral Drug R&D Field: Optical activity and chiral configuration detection of chiral drug molecules, drug intermediates and asymmetric synthetic products, judging drug chiral purity, and supporting drug synthesis process optimization and efficacy mechanism research. Organic Chiral Material Field: Circular dichroism characterization of chiral organic small molecules, chiral coordination compounds and asymmetric functional molecules, analyzing the absolute configuration and stereostructure characteristics of molecules. Supramolecular Assembly Field: Chiral signal test of chiral supramolecules, self-assembly systems and host-guest complexes, studying the chiral transmission, chiral amplification and structural evolution mechanism during the assembly process. Polymer Chiral Material Field: Conformational analysis of chiral polymers, helical polymers and optically active functional polymers, exploring the regulation law of polymerization process and modification methods on polymer chiral structures. Food and Natural Product Field: Optical activity detection of natural chiral extracts, active small molecules and food functional factors, providing data support for structural identification and activity mechanism research of natural products. Molecular Interaction Research Field: Characterizing the binding interaction of drug-protein, host-guest and polymer-small molecules, analyzing the changes of chiral structures before and after compounding, and exploring the mechanism of molecular recognition and interaction.