Mesoporous Solid-core Silica Nanoparticles(100-120 nm)

Product Name

Mesoporous Solid-core Silica Nanoparticles:00-120 nm)

^{Product Overview}

Mesoporous materials (pore size 2-50nm) have a pore size between microporous materials (pore size<2 nm) and macroporous materials (pore size>50 nm), and possess many excellent characteristics, such as highly ordered pore structure, single pore size distribution, and high stability, making them a hot research topic in recent years. As a common inorganic nanoparticle, silica nanoparticles have a series of advantages such as controllable morphology, ordered and adjustable pore structure, large specific surface area, easy modification of surface functional groups, and good biocompatibility, which make them widely used in biomedical, catalytic, environmental, optical and other fields. The main preparation method of silica nanoparticles is the sol gel method. Under the catalysis, the silicon source is formed by hydrolysis and condensation. This method was first proposed by Stober in 1968. According to the morphological characteristics of silica nanoparticles, they can be roughly divided into three types: solid silica, mesoporous silica, and hollow structured silica. Among them, the pore structure of mesoporous silica is generally formed by template method, which includes soft templates and hard templates. Soft templates are generally amphiphilic surfactants, while hard templates are generally high molecular weight polymers, with soft templates being more commonly used. The preparation process of mesoporous silicon can be divided into two stages: firstly, the template interacts with the inorganic precursor to synthesize liquid crystal structural phases with nanoscale lattice constants of organic and inorganic materials under certain conditions; Then, high-temperature heat treatment or other physical and chemical methods are used to remove the template, and the space left by the template forms mesoporous channels. The surface of silica nanoparticles has abundant silicon hydroxyl groups, which facilitate their surface chemical modification. By modifying different functional groups, silica nanoparticles can be endowed with more functions. The commonly used types of surface modifications currently include surface amination, thiolation, and organic chain functionalization. The surface modification of silica nanoparticles is mainly achieved by introducing different types of silane coupling agents, such as 3-aminopropyltriethoxysilane (APTES), which can be used for amination modification, and 3-mercaptopropyltrimethoxysilane, which can be used for thiol modification.    

^{Technical Parameter}

Status:White powder

Particle size:100-120 nm

Specific surface area:~570 m2/g

Average pore size:3-4 nm

Pore volume:0.35 cm2/g

(Note: The specific surface area is the data of a single test, allowing floating between different batches. For reference only, whichever is in kind.)

^{Product Features}

1) Multiple active sites: Due to its large specific surface area and abundant surface active sites, amination solid mesoporous silica nanoparticles can be used as catalyst carriers to improve the activity and selectivity of catalytic reactions.

2) Large specific surface area: due to the existence of mesoporous structure, it has a large specific surface area, which is conducive to adsorption and loading of drugs or other molecules.

3) Good hydrophilicity and biocompatibility: Amination improves the hydrophilicity and biocompatibility of nanoparticles, which contributes to their application in vivo.

Application Fields

1) Biomedicine: In the field of drug delivery, aminoated mesoporous silica nanoparticles can be used as drug carriers to achieve targeted drug delivery and controlled release;

2) Catalytic carrier: as a catalyst carrier, its high specific surface area and ordered pore structure are conducive to catalyst dispersion and mass transfer of reactants;

3) Adsorption separation: After surface amination, the surface of the nanoparticles has a positive charge, which helps to adsorb negatively charged substances, such as some pollutants and biomolecules;

^{Related Information}

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