
Product Name
Name:a>PLL coated Fe3O4 nanoparticles
Product Overview
Polylysine modified Fe3O4 magnetic nanoparticles are a composite material, and PLL modification on the surface of Fe3O4 nanoparticles can form Fe3O4@PLL Composite material, which combines the magnetic properties of Fe3O4 with the biocompatibility and multifunctionality of PLL.
Technical Parameter
Form: Brown black clear water colloid
Main components: PLL @ Fe3O4, pure water
Note: 5nm/10nm/20nm cannot be attracted by magnets and require magnetic separation columns to achieve magnetic separation.
Product Features
Superparamagnetism: Fe3O4 itself has superparamagnetism, which means they are magnetized in the presence of an external magnetic field, but once the magnetic field is removed, they quickly lose their magnetization state. This characteristic makes Fe3O4 nanoparticles very useful in biomedical applications, as they can be manipulated without generating permanent magnetization.
Biocompatibility: Polylysine (PLL) is a material with good biocompatibility that can reduce the immune response and toxicity of nanoparticles in vivo. This modification helps to improve the stability and safety of nanoparticles in vivo.
Targeted: PLL modification can enhance the binding ability of nanoparticles to specific cells or tissues, thereby achieving targeted drug delivery. This targeting is very important in cancer treatment and other disease treatments.
Stability: PLL modification can improve the stability of Fe3O4 nanoparticles in vivo, reduce their aggregation and degradation in vivo, and prolong their circulation time in vivo.
Application Fields
Magnetic resonance imaging (MRI): Iron oxide nanoparticles are widely used in magnetic resonance imaging due to their superparamagnetism and high magnetic susceptibility. Surface modified Fe3O4 nanoparticles can improve their biocompatibility and stability in vivo, thereby enhancing MRI imaging signals.
Magnetic hyperthermia (MHT): Under the action of an alternating magnetic field, Fe3O4 nanoparticles can generate heat for magnetic hyperthermia in cancer treatment. The modification of polylysine can enhance its targeting in tumor tissues, thereby improving therapeutic efficacy.
Drug delivery: Fe3O4 nanoparticles can introduce drug molecules through surface modification to achieve targeted drug delivery. The modification of polylysine can enhance its interaction with the cell membrane, improve drug targeting and bioavailability.
Cell targeting: Due to the biocompatibility of the PLL layer, it can bind to receptors on the cell membrane to achieve targeted recognition and treatment of specific cells. This modified Fe3O4 nanoparticle has potential applications in cell recognition and targeted therapy
Related Information
Please e-mail for the detailed characterization data.
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