Reactive oxygen responsive hydrogel

Product Name

^{Name: Reactive oxygen responsive hydrogel}

Product Overview

^{Reactive oxygen species (ROS) responsive hydrogel is a kind of innovative intelligent hydrogel, which is crosslinked by the ROS response module through covalent interaction, coordination interaction or supramolecular interaction. Due to the introduction of ROS response module, this kind of hydrogel is sensitive to the oxidative stress microenvironment in the organism. PVA-TSPBA hydrogel is a hydrogel formed by crosslinking polymerization of polyvinyl alcohol (PVA) and reactive oxygen sensitive crosslinking agent N1- (4-benzyl borate) - N3- (4-phenyl borate) N1, N1, N3, N3-tetramethyl-1,3-propanediamine (TSPBA). The hydrogel is composed of boric acid precursor (TSPBA) and PVA aqueous solution. The boric acid bond on TSPBA and the hydroxyl group on PVA quickly cross link to form borate ester bond to form hydrogel.}

^{Technical Parameter}

^{Solvent:Water}

^{Diameter:White or colorless gel}

^{Note: The concentration and volume ratio of PVA and TSPBA can be adjusted to meet different needs.}

^{Product Features}

^{1) High water absorption: the combination of PVA's water solubility and TSPBA's crosslinkability enables PVA-TSPBA hydrogel to maintain moisture and maintain its softness and elasticity.}

^{2) Biocompatibility: PVA, as a high molecular material with good biocompatibility, makes PVA-TSPBA hydrogel have low biological toxicity and immune reaction when applied in vivo.}

^{3) Controllability: By adjusting the ratio and polymerization conditions of PVA and TSPBA, the mechanical properties and water absorption of PVA-TSPBA hydrogel can be adjusted to meet different application needs.}

^{4) Reactive oxygen sensitive degradation characteristics: in the environment of high concentration of active oxygen, the borate ester bond is oxidized and broken, and the hydrogel gradually decomposes to achieve the goal of drug controlled release.}

^{Application Fields}

^{1) Drug controlled release: Utilizing its molecular recognition and response capabilities to capture and release specific drugs, thereby improving drug targeting and therapeutic efficacy.}

^{2) Biosensors: Biosensors that are sensitive to specific biomolecules can be constructed by introducing specific recognition elements into hydrogels.}

^{3) Tissue engineering: As a cell culture matrix or tissue repair material, it provides a suitable microenvironment for the growth and differentiation of cells.}

^{4) Wound dressing: By combining other antibacterial, antioxidant and other ingredients, excellent performance wound dressings can be developed to promote wound healing and prevent infection.}

^{Related Information}

^{Please e-mail for the detailed characterization data.}

E-mail:sales@xfnano.com