Product Name
Sulfhydryl Coated Fe3O4 Nanoparticles
Product Overview
Sulfhydryl-modified ferric tetraoxide magnetic nanoparticles are nanomaterials prepared by high temperature pyrolysis and surface modified by sulfhydryl functional groups.
Because of its stable material properties, better biocompatibility, higher strength, and no toxic side effects, ferric tetraoxide is widely used in magnetic resonance imaging, magnetic separation, targeted drug carriers, tumour thermotherapy technology, cell labelling and separation, and as an enhancement of developer, contrast agent research, retinal detachment repair surgery, etc., and can also be used as catalyst carriers, microwave absorbing materials, magnetic recording material. Xianfeng has made a lot of derivatives for this kind of magnetic particles, including oleic acid-modified ferric oxide, PEG-modified ferric oxide, DMSA-modified ferric oxide, polylysine-modified ferric oxide, carboxylated dextran-modified ferric oxide nanoparticles, streptavidin-modified ferric oxide particles, and sulfhydryl-modified ferric oxide magnetic nanoparticles, polyethyleneimine PEI-modified magnetic iron tetraoxide nanoparticles, and so on.
Technical Parameter
Appearance：Brown solution
Particle size：~5:0:0:0:0 nm（TEM:/span>
Concentration：~1 mg/mL
Note: The particle size is a single measurement result, and a small amount of deviation is allowed
Product Features
Superparamagnetism: Fe3O4 nanoparticles are inherently superparamagnetic and are capable of rapid magnetisation and demagnetisation under an applied magnetic field, which is critical for applications such as magnetic resonance imaging (MRI) and magnetic hyperthermia (MHT). Sulfhydryl functionalization: Through sulfhydryl (-SH) modification, active functional groups are introduced on the surface of the nanoparticles, which facilitates covalent binding with biomolecules (e.g., proteins, antibodies, drugs, etc.) and enhances their functionality in biological systems.
Biocompatibility: sulfhydryl modification can improve the biocompatibility of nanoparticles and reduce the toxicity to normal cells and tissues, making them more suitable for biomedical applications.
Stability: The introduction of sulfhydryl groups can improve the stability of nanoparticles in living organisms, reduce agglomeration and oxidation, and prolong their residence time in the blood circulation.
Targeting: sulfhydryl-modified nanoparticles can bind to targeting ligands through specific chemical linkages to achieve targeting of specific cells or tissues and improve the precision of treatment.
Application Fields
Magnetic Resonance Imaging (MRI): sulfhydryl-modified iron tetraoxide nanoparticles can be used as a contrast agent in MRI to enhance the imaging signal. Due to their superparamagnetic properties, these nanoparticles are able to reduce the relaxation time of the surrounding protons, thus improving the clarity and accuracy of imaging.
Drug delivery: these nanoparticles can be used as drug carriers to deliver drugs precisely to the tumour site by applying a magnetic field. Sulfhydryl modification improves the biocompatibility and stability of the nanoparticles, giving them a longer circulation time in the body, thus improving drug targeting and therapeutic efficacy.
Magnetothermal therapy (MHT): Under the action of an applied alternating magnetic field, sulfhydryl-modified iron tetroxide nanoparticles are able to generate local high temperatures, thereby killing tumour cells. This treatment method has the advantages of high biosafety and deep tissue penetration.
Cell separation and labelling: due to their magnetic properties and sulfhydryl modification, these nanoparticles can be used for cell separation and labelling. For example, specific binding of sulfhydryl groups to cell surface molecules enables separation and detection of specific cell types.
Related Information
Sealed, avoid light, and keep at 4¡ãC Expiry date: six months.
Please e-mail for the detailed characterization data.
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